Page last updated: 2024-11-12

5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

penflufen: Fungicides, Industrial [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

penflufen : A racemate comprising equimolar amounts of (R)- and (S)-penflufen. A fungicide used in furrow and seed piece treatment use on potatoes and as a seed treatment for legume vegetables, cereal grains, oil seeds and alfalfa. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide : An aromatic amide obtained by formal condensation of the carboxy group of 5-fluoro-1,3-dimethylpyrazole-4-carboxylic acid with the amino group of 2-(4-methylpentan-2-yl)aniline. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID11674113
CHEBI ID83134
SCHEMBL ID69448

Synonyms (24)

Synonym
5-fluoro-1,3-dimethyl-n-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide
GOFJDXZZHFNFLV-UHFFFAOYSA-N
n-[2-(1,3-dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1h-pyrazole-4-carboxamide
SCHEMBL69448
penflufen
pyflufen
penflufen, (+/-)-
5-fluoro-1,3-dimethyl-n-(2-(1,3-dimethylbutyl)phenyl)-1h-pyrazole-4-carboxamide
494793-67-8
2'-((rs)-1,3-dimethylbutyl)-5-fluoro-1,3-dimethylpyrazole-4-carboxanilide
unii-8252e275kt
n-(2-(1,3-dimethylbutyl)phenyl)-1,3-dimethyl-5-fluoro-1h-pyrazole-4-carboxamide
8252e275kt ,
5-fluoro-1,3-dimethyl-n-[2-(4-methylpentan-2-yl)phenyl]-1h-pyrazole-4-carboxamide
CHEBI:83134
DTXSID9058107
penflufen [mi]
penflufen, pestanal(r), analytical standard
CS-0181227
Q16736519
penflufen 100 microg/ml in acetonitrile
EN300-225324
1h-pyrazole-4-carboxamide, n-[2-(1,3-dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-
HY-139161

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Based on the toxic unit analysis, the toxic interactions of antagonistic effect and concentration addition were found between penflufen enantiomers, indicating the coexistence of R-(-)-penflufen could increase overuse and environmental risks."( Enantioselective toxicity and mechanism of chiral fungicide penflufen based on experiments and computational chemistry.
Cang, T; Di, S; Qi, P; Wang, X; Wang, Z; Xie, Y; Xu, H; Zhao, H, 2021
)
0.62
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (3)

ClassDescription
aromatic amideAn amide in which the amide linkage is bonded directly to an aromatic system.
organofluorine compoundAn organofluorine compound is a compound containing at least one carbon-fluorine bond.
pyrazoles
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's5 (71.43)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]